| Product Name | Myosin skeletal H&L chains antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Myosin Skeletal Heavy and Light chainsMyosin is a 480,000 dalton protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons). Myosin molecules consist of two major regions: tails (rods) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch). Type II fibers can be further subdivided in types IIA, IIB, and IIC. |
| Immunogen | Full length native protein (purified) (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IF |
| IF: Use at a dilution of 1/20. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Target | Myosin skeletal H&L chains |
|---|---|
| Tissue Specificity | The product does not react with human smooth muscle myosin. is specific for the A band of human skeletal myosin by indirect immunofluorescent labeling. |
| Cellular Localization | Cytoplasmic |
| Application Notes | IF: Use at a dilution of 1/20. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: Whole Serum |
