| Product Name | Myosin VI antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit anti-Myosin-VI polyclonal antibodyMyosin-VI is one of the unconventional members of the myosin molecular motor superfamily. The protein has broad tissue expression and has been implicated in endocytosis at both the clathrin-coated and uncoated stages. Regulation of myosin-6 transport has been shown to involve adaptor proteins including GIPC, which contains a PDZ-domain for uncoated vesicle recruitment and Dab2 for clathrin-coated vesicle association. In hair cells of the inner ear, absence of functional myosin-VI protein leads to cell death and deafness. |
| Immunogen | Rabbits were immunized with amino acids 1049-1054 from the tail region of porcine myosin-VI. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| IF (5-10 ug/ml), WB (0.5-1.0 ug/ml: |
|
| Species Reactivity | Pig |
| Concentration | 1mg/ml |
| Target | Myosin VI |
|---|
| Application Notes | IF (5-10 ug/ml), WB (0.5-1.0 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20º C. Avoid multiple freeze/thaw cycles. |
| Storage Buffer | 50 ug (0.5 mg/ml) of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. |
