Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using Myotilin antibody at 1:500 dilution.Application
Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE diluted at 1:3000| Product Name | Myotilin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Myotilin (myotilin)This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Myotilin. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Pig, BovineMouse (93%), Rat (94%), Pig (95%), Bovine (95%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | LGMD1 antibody LGMD1A antibody TTID antibody MYOT antibody myotilin antibody titin immunoglobulin domain protein (myotilin) antibody 57 kDa cytoskeletal protein antibody myofibrillar titin-like Ig domains protein antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa (note) (3) |
| Cellular Localization | Cell membrane , sarcolemma , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk |
Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using Myotilin antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE diluted at 1:3000| Positive Control | A549 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
