Application
Western Blot: NBS1 Antibody - Detection of Human NBS1 on HeLa whole cell lysate using .| Product Name | NBS1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to p95 NBS1The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions. |
| Immunogen | A synthetic peptide, which represented a portion of human Nijimegen breakage syndrome 1 encoded in part by exons 12 and 13. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000 - 1/10000. Predicted molecular weight: 90 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | AT V1 AT V2 ATV NBS Nibrin Nijmegen breakage syndrome p95 |
|---|---|
| Target | NBS1 |
| Cellular Localization | Nuclear |
Application
Western Blot: NBS1 Antibody - Detection of Human NBS1 on HeLa whole cell lysate using .| Positive Control | HeLa nuclear extract |
|---|---|
| Application Notes | IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000 - 1/10000. Predicted molecular weight: 90 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: Tris citrate/phosphate. pH 7-8 |
