Application
IHC-P analysis of human heart tissue using NR2C antibody at 1:100. Left to right:DAPI, GRIN2C, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer.Application
WB analysis of Jurkat cells using NR2C antibody at 0.2-1μg/ml.| Product Name | NDMAR2C antibody, N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NR2CThis gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
| Immunogen | A synthetic peptide corresponding to a N-terminal region of Human NR2C |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 79% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NMDAR2C GLUN2C NR2C GRIN2C |
|---|---|
| Target | NR2C |
| Molecular Weight(MW) | 134 KDa (note) |
Application
IHC-P analysis of human heart tissue using NR2C antibody at 1:100. Left to right:DAPI, GRIN2C, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer.
Application
WB analysis of Jurkat cells using NR2C antibody at 0.2-1μg/ml.| Positive Control | Jurkat |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
