N-methyl-D-aspartate (NMDA) receptors are a class of
ionotropic glutamate receptors. NMDA channel has been shown to be
involved in long-term potentiation, an activity-dependent increase
in the efficiency of synaptic transmission thought to underlie
certain kinds of memory and learning. NMDA receptor channels are
heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and
1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B
(GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by
RefSeq].1) Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Immunogen
This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.