Rabbit polyclonal antibody to Nectin 2 (poliovirus receptor-related 2 (herpesvirus entry mediator B))This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Nectin 2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (80%), Rat (80%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CD112 antibody HVEB antibody PRR2 antibody PVRR2 antibody PVRL2 antibody nectin-2 antibody herpesvirus entry protein B antibody poliovirus receptor-related protein 2 antibody poliovirus receptor-like 2 antibody poliovirus receptor-related 2 (herpe
Target
PVRL2(CD112)
Molecular Weight(MW)
58 kDa (note)
Cellular Localization
Cell membrane; Single-pass type I membrane protein
Application
Application
Sample(30 μg of whole cell lysate) A:293T 10% SDS PAGE diluted at 1:500
Positive Control
293T
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.