| Product Name | Neisseria gonorrhoeae antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Neisseria gonorrhoeaeNeisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn). |
| Immunogen | Whole Neisseria gonorrhoeae. ATCC 31426 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ConjugationELISAICC/IF |
| Conjugation: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC/IF: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Bacteria |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | N. gonorrhoeae |
|---|---|
| Target | Neisseria gonorrhoeae |
| Tissue Specificity | Reacts to all antigens of Neisseria gonorrhoeae. Antiserum is not absorbed and may react with related microorganisms. |
| Application Notes | Conjugation: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC/IF: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containing 0.1% sodium azide |
