| Product Name | Neisseria gonorrhoeae antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [801] to Neisseria gonorrhoeaeNeisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn). |
| Immunogen | Pool of UV-inactivated Neisseria gonorrhoeae cells: Neisseria Reference Laboratory strains G-7, R-11 and 71222 (W-I), 5766 and 8038 (W-II), 8660 (W-III). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 801 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| Recommended dilutions: ELISA: May be used to detect and quantitate N. gonorrhoeae. Use at an assay dependent dilution. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | N. gonorrhoeae |
|---|---|
| Target | Neisseria gonorrhoeae |
| Application Notes | Recommended dilutions: ELISA: May be used to detect and quantitate N. gonorrhoeae. Use at an assay dependent dilution. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: PBS. pH 7.4 |
