Rabbit Polyclonal antibody to Neuropeptide BNeuropeptide B is a endrogenous ligand of the orphan G protein coupled receptor GPR7. NPB and GPR7 exist in close proximity in the rat hypothalamus, and are ideally positioned to modulate neuroendocrine functions. NPB-immunoreactivity was enriched in many regions within the hypothalamus which also contained high levels of GPR7 mRNA including the ventrormedial hypothalamic nucleus, dorsomedial hypothalamic nucleus, arcuate nucleus, supraoptic retrochiasmatic nucleus, and in the area ventral to the zona incerta.
Immunogen
Synthetic peptide corresponding to residues W(1) Y K P A A G P H H Y S V G R A S G L L S S F H R F P S T(29) of mouse NPB protein.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ICC/IFIHCWB
ICC/IF: 1 µg/ml:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NPB PPL7 PPNPB neuropeptide B
Target
Neuropeptide B
Application
Application
IHC analysis of colchicine-treated rat hypothalamus tissue using Neuropeptide B antibody.
Application Notes
ICC/IF: 1 µg/ml:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.