Rabbit polyclonal antibody to Neurotrophin 3The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Neurotrophin 3 (174-189aa TVLGEIKTGNSPVKQY), identical to the related rat and mouse sequences.
Conjugation
Agarose
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIFIHC-PWB
IF:1:100~1:200 IHC-P:1:20~1:100 WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMonkeyMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NT3 NGF2 HDNF neurotrophin 3 NGF-2
Target
NTF3
Application
Application
IHC-P analysis of rat brain tissue using Neurotrophin 3 antibody.
Application
WB analysis of indicated lysates using Neurotrophin 3 antibody.
Application Notes
IF:1:100~1:200 IHC-P:1:20~1:100 WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC. Avoid multiple freeze-thaw cycles.