Application
NKG2D antibody detects NKG2D protein by western blot analysis. Human tissue extracts (30 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with NKG2D antibody at a dilution of 1:1000.Application
NKG2D antibody [N3C2], Internal detects NKG2D protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. NKG2D antibody [N3C2], Internal dilution: 1:250.| Product Name | NKG2D antibody , Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NKG2D (killer cell lectin-like receptor subfamily K, member 1)Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human NKG2D. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | ChimpanzeeChimpanzee (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD314 antibody D12S2489E antibody FLJ17759 antibody FLJ75772 antibody KLR antibody NKG2-D antibody NKG2D antibody KLRK1 antibody NK cell receptor D antibody NKG2-D-activating NK receptor antibody NKG2-D type II integral membrane protein antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa (note) |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
Application
NKG2D antibody detects NKG2D protein by western blot analysis. Human tissue extracts (30 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with NKG2D antibody at a dilution of 1:1000.
Application
NKG2D antibody [N3C2], Internal detects NKG2D protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. NKG2D antibody [N3C2], Internal dilution: 1:250.| Positive Control | human spleen |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
