Rabbit polyclonal antibody to NKIRAS1 (NFKB inhibitor interacting Ras-like 1)Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Immunogen
Recombinant protein encompassing a sequence within the center region of human kappaB-Ras1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Predicted Reactivity
Human, Mouse, Rat, Rhesus Monkey, ChimpanzeeHuman (100%), Mouse (95%), Rat (95%), Rhesus Monkey (100%), Chimpanzee (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
KBRAS1 antibody kappaB-Ras1 antibody NKIRAS1 antibody I-kappa-B-interacting Ras-like protein 1 antibody NF-kappa-B inhibitor-interacting Ras-like protein 1 antibody kappa B-Ras protein 1 antibody NFKB inhibitor interacting Ras-like protein 1 antibody
Target
kappaB-Ras1
Molecular Weight(MW)
22 kDa (note)
Cellular Localization
Cytoplasm
Positive Control
Target recombinant protein
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.