Mouse monoclonal antibody [2E1] to Nkx2.5This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Immunogen
The immunogen corresponding to human Nkx2.5 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2E1
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
NKX4-1 VSD3 HLHS2 CSX1 NKX2E CHNG5 CSX NKX2-5
Target
Nkx2.5
Molecular Weight(MW)
35 kDa (note)
Application
Application
Western blot analysis using anti-NKX2.5 mAb against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.
Storage Buffer
Antibody are purified by protein G affinity chromatography. Liquid in PBS containing 0.03% sodium azide.