Rabbit polyclonal to NKX3.1NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis. NKX3.1 expression is dramatically down-regulated in testicular cancer of germ cell origin. Results suggest that NKX3.1 is essential for normal testis function and that its loss of expression is highly associated with the invasive phenotype of testicular germ cell tumors.
Immunogen
Peptide: TPSKPLTSFLIQDILRD
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blot - Use at 1:1,000 dilution. May be diluted up to 1:5,000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.:
Species Reactivity
MouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
NKX 3.1 3 NKX3
Target
NKX3.1
Tissue Specificity
Reacts with residues 21-37 (TPSKPLTSFLIQDILRD) of human NKX3.1
Application Notes
Western blot - Use at 1:1,000 dilution. May be diluted up to 1:5,000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.