Application
Western blot of HEK293 cells using expressing: 1. without NR1 expression 2. NR1 subunit containing only the C2 insert 3,4. NR1 subunit containing C1/C2' and N1/C2' insert| Product Name | NMDAR1 (splice variant C2) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to NMDA NR1 Subunit, Splice Variant C2NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit, C2 splice variant insert conjugated to KLH |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NMDAR1 GRIN1 glutamate receptor ionotropic N-methyl D-aspartate 1 NMDA receptor 1 NR1 N-methyl-D-aspartate receptor channel subunit zeta-1 glutamate [NMDA] receptor subunit zeta NMDA receptor1 glutamate receptor ionotropic Nmethyl Daspartate1 |
|---|---|
| Target | NMDAR1, Splice Variant C2 |
| Molecular Weight(MW) | 120 (note) |
| Cellular Localization | Enriched in post-synaptic plasma membrane and post-synaptic densities. |
Application
Western blot of HEK293 cells using expressing: 1. without NR1 expression 2. NR1 subunit containing only the C2 insert 3,4. NR1 subunit containing C1/C2' and N1/C2' insert| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
