Application
NMDAR1 antibody detects NMDAR1 protein expression by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: NMDAR1 protein stained by NMDAR1 antibody diluted at 1:250. Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] diluted at 1:250. Blue: Fluoroshield with DAPI .Application
NMDAR1 antibody detects NMDAR1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. NMDAR1 antibody diluted at 1:400.Application
Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with NMDAR1 antibody diluted at 1:1000.| Product Name | NMDAR1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NMDAR1 (glutamate receptor, ionotropic, NMDA1 (zeta 1))NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Modulated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse NMDAR1. The exact sequence is proprietary. |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICCICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | Human, DogHuman (100%), Dog (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GluN1 antibody GluRdelta1 antibody GluRzeta1 antibody Grin1 antibody M100174 antibody NMDAR1 antibody NMDAR1 antibody NR1 antibody Nmdar antibody Rgsc174 antibody glutamate receptor ionotropic NMDA1 (zeta 1) antibody |
|---|---|
| Target | NMDAR1 |
| Molecular Weight(MW) | 105 kDa (note) (3) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity) , Cell junction , synapse , postsynaptic cell membrane (By similarity) , postsynaptic cell membrane , postsynaptic density (By similarity) |
Application
NMDAR1 antibody detects NMDAR1 protein expression by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: NMDAR1 protein stained by NMDAR1 antibody diluted at 1:250. Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] diluted at 1:250. Blue: Fluoroshield with DAPI .
Application
NMDAR1 antibody detects NMDAR1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. NMDAR1 antibody diluted at 1:400.
Application
Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with NMDAR1 antibody diluted at 1:1000.| Positive Control | mouse brain , mouse fetal brain , rat brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
