Application
WB analysis of mouse lung extract using NOD1 antibody.Application
IHC-P analysis of human kidney using NOD1 antibody at a dilution of 1:200.Application
IHC-P analysis of human liver using NOD1 antibody at a dilution of 1:200.Application
IHC-P analysis of human rectal cancer using NOD1 antibody at a dilution of 1:200.| Product Name | NOD1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NOD1This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009] |
| Immunogen | Recombinant protein of human NOD1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:100 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | nucleotide-binding oligomerization domain containing 1 , NLRC1 , CARD4 , CLR7.1 |
|---|---|
| Target | NOD1 |
| Molecular Weight(MW) | 108 kDa (note) |
Application
WB analysis of mouse lung extract using NOD1 antibody.
Application
IHC-P analysis of human kidney using NOD1 antibody at a dilution of 1:200.
Application
IHC-P analysis of human liver using NOD1 antibody at a dilution of 1:200.
Application
IHC-P analysis of human rectal cancer using NOD1 antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
