Application
Immunofluorescence of NOD5 in rat spleen tissue with NOD5 antibody at 20 μg/mL.Application
Immunohistochemistry of NOD5 in rat spleen tissue with NOD5 antibody at 10 μg/mL.| Product Name | NOD5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to NOD5NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-P |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NOD26, Nucleotidebinding oligomerization domain containing 5, NLRX1, Nucleotidebinding oligomerization domain containing5, NOD9, Nucleotide-binding oligomerization domain containing 5, CLR11.3, DLNB26, NOD5 |
|---|---|
| Target | NOD5 |
| Tissue Specificity | This antibody is specific for NOD5 |
Application
Immunofluorescence of NOD5 in rat spleen tissue with NOD5 antibody at 20 μg/mL.
Application
Immunohistochemistry of NOD5 in rat spleen tissue with NOD5 antibody at 10 μg/mL.| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
