Application
Western blot analysis on (A) MCF-7, (B) HepG2, and (C) Caco-2 cell lysates using anti-gp91-phox RabMAb .| Product Name | NOX2 / gp91phox antibody [EPR6991] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Monoclonal antibody to NOX2/gp91phoxgp91-phox, or Cytochrome b, is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. |
| Immunogen | A synthetic peptide corresponding to residues in human NOX2/gp91phox was used as an immunogen. |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR6991 |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX |
|---|---|
| Target | NOX2/gp91phox |
Application
Western blot analysis on (A) MCF-7, (B) HepG2, and (C) Caco-2 cell lysates using anti-gp91-phox RabMAb .| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS (pH 7.2), 0.01% sodium azide, 50% Glycerol and 0.05% BSA. |
