Rabbit polyclonal antibody to NPY1RNeuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]).[supplied by OMIM, Mar 2008]
Immunogen
The immunogen corresponding to a region within amino acids 301 and 382 of Human NPY1R.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFIHC-PWB
P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Species Reactivity
HumanMouseDogPigRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NPYR neuropeptide Y receptor Y1 NPY1-R
Target
NPY1R
Application
Application
IHC analysis of rat myocardium tissue using NPY1-R antibody.
Application
Immunohistochemical analysis of formalin fixed and paraffin embedded rat brain tissue using NPY1R antibody
Application Notes
P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Storage Buffer
10 mM PBS, pH 7.4 with 10 mg/ml BSA, 0.03% Proclin 300 and 25% glycerol