Application
Immunohistochemical staining of human tissue sections using NR2E3 antibody| Product Name | NR2E3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to NR2E3NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye. The ligand for the receptor is unknown at present. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC-P: Use at a dilution of 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Target | NR2E3 |
|---|---|
| Cellular Localization | Nuclear |
Application
Immunohistochemical staining of human tissue sections using NR2E3 antibody| Application Notes | IHC-P: Use at a dilution of 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.01% Sodium Azide; Constituents: PBS. pH 7.4 |
