Rabbit Polyclonal antibody to NRG2This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010]
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Neuregulin 2, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
neuregulin 2 NTAK HRG2 DON1
Target
NRG2
Application
Application
Lane 1: Rat Liver Tissue Lysate Lane 2: COLO320 cell Lysate Lane 3: SMMC cell Lysate Lane 4: SW620 cell Lysate
Application Notes
WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC. Avoid multiple freeze-thaw cycles.