Mouse monoclonal antibody [4G5] to NTRK3This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Immunogen
The immunogen corresponding to a region within amino acids 32 and 429 of human NTRK3 fused with hIgGFc tag expressed in HEK293 cells.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4G5
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
GP145(TRKC) TRKC
Target
NTRK3
Molecular Weight(MW)
94 kDa (note)
Application
Application
Western blot analysis using anti-NTRK3 monoclonal antibody against extracellular domain of human NTRK3 (aa32-429).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.