Rabbit Polyclonal antibody to NUAK2 (NUAK family, SNF1-like kinase, 2)Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
Immunogen
Recombinant protein encompassing a sequence within the center region of human NUAK2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (94%), Rat (93%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)