Application
IHC-P analysis of human small intestine tissue using OAS1 antibody at 5μg/ml.Application
WB analysis of human fetal stomach tissue using OAS1 antibody at 0.2-1μg/ml.| Product Name | OAS1 antibody, N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to OAS1This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthetic peptide corresponding to a N-terminal region of Human OAS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | OAS1 OIASI IFI4 OIAS |
|---|---|
| Target | OAS1 |
| Molecular Weight(MW) | 46 KDa (note) |
Application
IHC-P analysis of human small intestine tissue using OAS1 antibody at 5μg/ml.
Application
WB analysis of human fetal stomach tissue using OAS1 antibody at 0.2-1μg/ml.| Positive Control | human fetal stomach |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
