Rabbit Polyclonal antibody to OATP2This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]
Immunogen
SLCO1B1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLCO1B1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 - 2 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
LST1 SLCO1B1 LST-1 HBLRR OATP-C solute carrier organic anion transporter family member 1B1 OATPC OATP1B1 SLC21A6
Target
OATP2
Tissue Specificity
SLCO1B1 antibody is human specific. At least four isoforms of SLCO1B1 are known to exist. This antibody is predicted to not cross-react with other SLCO1B proteins.
Application
Application
Western blot analysis of SLCO1B1 in human liver tissue lysate with SLCO1B1 antibody at 1 ug/ml.
Application Notes
WB: 1 - 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year.