Rabbit polyclonal antibody to OCC-1OCC-1 (Overexpressed in colon carcinoma-1) was initially identified as a novel human cDNA overexpressed in a colon carcinoma cell line. Elevated levels of OCC-1 mRNA were observed in three of eight colon carcinomas, suggesting that OCC-1 may be a hallmark of only a subset of colon carcinomas. It is highly expressed in skeletal muscle, kidney, placenta, and pancreas tissues, with low to no expression in heart, brain, lung and liver tissues. At least two different OCC-1 mRNA species are known to exist. In vitro transcription and translation of the OCC-1 cDNA yields polypeptides less than 9 kDa. Despite this, OCC-1 from cell lines is detected at ~28 kDa in SDS-PAGE.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
OCC-1 Overexpressed in colon carcinoma-1 OCC1 Overexpressed in colon carcinoma1 OCC 1
Target
OCC-1
Tissue Specificity
This antibody is specific for OCC-1 N-Terminus
Application
Application
Western blot analysis of OCC-1 in human spleen tissue lysate with OCC-1 antibody at 2 ug/ml.
Application
Immunohistochemistry of OCC-1 in human spleen tissue with OCC-1 antibody at 2.5 ug/ml.