Rabbit polyclonal antibody to OCIAD2OCIAD2 was identified by its sequence similarity with OCIAD1, and together OCIAD1 and OCIAD2 form the OCIA domain family. OCIAD2 mRNA was found to be expressed at higher levels in invasive adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component (BAC) of the lung. Loss of OCIAD2 expression was significantly correlated with lymphatic invasion, blood vessel invasion, and lymph node metastasis, indicating that OCIAD2 may play a role in cell adhesion and prevention of cell migration. While the function of OCIAD2 is still unknown, its expression in adenocarcinoma with BAC component is significantly associated with a favorable prognosis and may serve as a marker for selecting tumors that are treatable by limited surgery.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
OCIA domaincontaining protein 2 OCIA domain-containing protein 2 OCIAD2 Ovarian cancer immuno-reactive antigen domain-containing protein 2 Ovarian cancer immunoreactive antigen domaincontaining protein2 OCIA domaincontaining protein2 Ovarian cancer i
Target
OCIAD2
Tissue Specificity
This antibody is specific for OCIAD2 N-Terminus
Application
Application
Immunofluorescence of OCIAD2 in A549 cells with OCIAD2 antibody at 20 ug/ml.
Application
Western blot analysis of OCIAD2 in SK-N-SH cell lysate with OCIAD2 antibody at (A) 0.5 and (B) 1 ug/ml.