Application
Whole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with OPA1 antibody diluted at 1:1000.| Product Name | OPA1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to OPA1 (optic atrophy 1 (autosomal dominant))This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human OPA1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, BovineMouse (100%), Rat (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NTG MGM1 optic atrophy 1 (autosomal dominant) NPG largeG |
|---|---|
| Target | OPA1 |
| Molecular Weight(MW) | 112 kDa (note) (8) |
| Cellular Localization | Mitochondrion inner membrane; Single-pass membrane protein , Mitochondrion intermembrane space |
Application
Whole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with OPA1 antibody diluted at 1:1000.| Positive Control | APRE19 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
