| Product Name | OPG antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [7D37] to OsteoprotegerinThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant TNFRSF11B |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7D37 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-1000)|Neutralization of soluble TNFRSF11B bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | tumor necrosis factor receptor superfamily member 11b OCIF OPG TR1 |
|---|---|
| Target | TNFRSF11B |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human Osteoprotegerin |
| Application Notes | WB(1:500-1000)|Neutralization of soluble TNFRSF11B bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
