Rabbit Polyclonal antibody to OSBP2 (oxysterol binding protein 2)Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human OSBP2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (92%), Rat (93%), Bovine (91%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
ORP-4 antibody ORP4 antibody OSBPL1 antibody OSBPL4 antibody OSBP2 antibody OSBP-related protein 4 antibody oxysterol-binding protein-related protein 4 antibody oxysterol binding protein-like 1 antibody oxysterol binding protein-related protein 4 a
Molecular Weight(MW)
101 kDa (note) (7)
Cellular Localization
Membrane; Peripheral membrane protein
Application
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using OSBP2 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1 , IMR32 , MCF-7
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.