Rabbit polyclonal antibody to OsteopontinThe protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
Immunogen
KLH conjugated synthetic peptide derived from mouse OPN C-terminus
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P(1:100-500):
Species Reactivity
Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
BNSP 2AR RIC SPP-1 SPP1 BSPI OPN ETA ETA-1 OP OPNL BSP APL-1
Target
Osteopontin
Tissue Specificity
OPN/BSP
Application
Application
IHC-P analysis of rat hippocampus using Osteopontin antibody at a dilution of 1:300.
Application
IHC-P analysis of rat shin bone using Osteopontin antibody at a dilution of 1:300.
Application Notes
IHC-P(1:100-500):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.