| Product Name | p120 Catenin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [6H11] to p120 Catenindelta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. |
| Immunogen | GTX11508 is derived from the 6H11 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an A/J mouse immunized with a recombinant N-terminal fragment of murine delta 1 Catenin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6H11 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIPWB |
| ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IF: Use at a dilution of 1/100. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10000. Detects a band of approximately 120 kDa (and a possible doublet band of approximately 200 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseChickenDogRatBovine |
| Concentration | 1mg/ml |
| Gene Synonyms | delta1 Catenin AA409437 P120 601045 P120CTN AU019353 Ctnnd KIAA0384 CAS O60716 P120CAS delta 1 Catenin Catns CTNND1 1500 12388 mKIAA0384 |
|---|---|
| Target | p120 Catenin |
| Positive Control | Tested with Madin Darby canine kidney (MDCK) epithelial cells and whole cell extract from cultured chicken fibroblasts |
|---|---|
| Application Notes | ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IF: Use at a dilution of 1/100. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10000. Detects a band of approximately 120 kDa (and a possible doublet band of approximately 200 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 15mM Sodium Azide; Constituents: Tissue Culture Supernatant |
