| Product Name | p21 Cip1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to p21 Cip1Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and over expression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control. |
| Immunogen | Synthetic peptide: GRKRRQTSMTDFYHSKRRLIFSKRKP , corresponding to amino acids 139-164 of Human p21. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/250 - 1/500. Detects a band of approximately 21 kDa (predicted molecular weight: 19.7 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 MDA 6 MDA6 |
|---|---|
| Target | p21 Cip1 |
| Cellular Localization | Nuclear |
| Application Notes | WB: Use at a dilution of 1/250 - 1/500. Detects a band of approximately 21 kDa (predicted molecular weight: 19.7 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02mM Sodium Azide; Constituents: 40% Glycerol, PBS. pH 7.2 |
