| Product Name | p21 Cip1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody to p21 Cip1Monoclonal Mouse Anti-Human WAF1/p21 Protein |
| Immunogen | Human p21 protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | B459 |
| Host Species | Mouse |
| Tested Applications | IHC-FIHC-P |
| Immunohistochemistry 1:50-1:100 on tissue sections. This antibody can be used on frozen and formalin-fixed paraffin-embedded tissue sections. When using on formalin-fixed paraffin-embedded tissues a antigen demasking procedure is recommended. The antibody may be used at a dilution of 1:50-1:100 with AutoProbe III (GTX28620). The optimal conditions should be determined by the individual laboratory.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CDKN1A 116899 1026 P21 P38936 MDA-6 SDI1 MDA6 p21CIP1 CIP1 CDKN1 WAF1 CAP20 MDA 6 |
|---|---|
| Target | p21 Cip1 |
| Tissue Specificity | This antibody reacts with human and other mammalian p21 protein. p21 is an intracellular protein of 21kD size. It is also known as the wild type p53 activated fragment 1 or WAF1. p21 inhibits cyclin-dependent kinases (Cdk's) and also proliferating cell nuclear antigens or PCNA's). |
| Cellular Localization | Nuclear |
| Positive Control | Breast, Skin, or Colon Carcinoma, Fibroadenoma |
|---|---|
| Application Notes | Immunohistochemistry 1:50-1:100 on tissue sections. This antibody can be used on frozen and formalin-fixed paraffin-embedded tissue sections. When using on formalin-fixed paraffin-embedded tissues a antigen demasking procedure is recommended. The antibody may be used at a dilution of 1:50-1:100 with AutoProbe III (GTX28620). The optimal conditions should be determined by the individual laboratory.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | PBS buffer with 0.1% sodium azide |
