Application
DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange| Product Name | P2X3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to P2X3The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. |
| Immunogen | Synthetic peptide: VEKQSTDSGAYSIGH, corresponding to amino acids 383-397 of C-terminus of Rat P2X3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-FWB |
| ICC: Use at a dilution of 1/1000. IHC-Fr: Use at a dilution of 1/1000. WB: Use at a dilution of 1/1000. Predicted molecular weight: 47.6 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRatPrimate |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Target | P2X3 |
|---|---|
| Cellular Localization | Plasma membrane |
Application
DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange| Application Notes | ICC: Use at a dilution of 1/1000. IHC-Fr: Use at a dilution of 1/1000. WB: Use at a dilution of 1/1000. Predicted molecular weight: 47.6 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: Whole Serum |
