Rabbit polyclonal to P2Y6P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen,and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
Immunogen
Synthetic peptide KLH conjugated (unfortunately, the amino acid sequence is considered to be commercially sensitive)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHCIHC-P
ICC: Use at an assay dependent dilution. IHC-P: Use at a dilution of 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
G coupled nucleotide receptor G protein coupled 6 MGC15335 P2 purinoceptor P2RY6 P2Y purinoceptor 6 P2Y6 receptor Purinergic receptor P2Y6 pyrimidinergic receptor P2Y
Target
P2Y6
Cellular Localization
Integral plasma membane protein.
Application
Application
Cells expressing target protein - immunostained with target antibody
Positive Control
Placenta, villi
Application Notes
ICC: Use at an assay dependent dilution. IHC-P: Use at a dilution of 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.