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p38 MAPK antibody

Catalog Number:OM266979
OM266979
Discount Price
OM266979-100ul
1~2 Week
100ul
OM266979-50ul
50ul
1~2 Week
Product Profile
Product Name p38 MAPK antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [8G4D11] to p38 MAPKThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to a region within amino acids 299 and 360 of human MAPK14 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 8G4D11
Host Species Mouse
Tested Applications ELISAFACSICC/IFIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms CSBP
MXI2
CSPB1
MAPK14
CSBP2
P38ALPHA
SAPK2A
PRKM14
CSBP1
P38
PRKM15
RK
EXIP
Target p38 MAPK
Molecular Weight(MW) 41.3 kDa (note)
Application

Application

IHC-P analysis of rectum cancer tissues using p38 MAPK antibody [8G4D11].

Application

IHC-P analysis of cervical cancer tissues using p38 MAPK antibody [8G4D11].

Application

FACS analysis of HeLa cells using p38 MAPK antibody [8G4D11] (green) or a negative control (red).

Application

ICC/IF analysis of HeLa cells using p38 MAPK antibody [8G4D11] (green), Alexa Fluor-555 phalloidin (red) and DRAQ5 fluorescent DNA dye (blue).

Application

ELISA analysis of control antigen and antigen using p38 MAPK antibody [8G4D11].

Application

WB analysis of lysates from (1) untransfected and (2) MAPK14 (a.a. 299-360)-hIgGFc transfected HEK293 cells using p38 MAPK antibody [8G4D11].

Application

WB analysis of (1) HeLa, (2) NIH3T3, (3) Jurkat, Raw264.7 (4), (5) PC-12, (6) C6 and (7) COS7 lysates using p38 MAPK antibody [8G4D11].

Application

WB analysis of human MAPK14 recombinant protein using p38 MAPK antibody [8G4D11].
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
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