Application
Immunofluorescence of CDKN1C in 293 cells with CDKN1C antibody at 20 ug/mL.Application
Western blot analysis of CDKN1C in 293 cell lysate with CDKN1C antibody at (A) 1 and (B) 2 ug/mL.| Product Name | p57 Kip2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to p57 Kip2This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| Immunogen | CDKN1C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDKN1C. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| WB: 1 - 2 ug/ml. IF: 20 ug/ml: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | WBS KIP2 BWS cyclin-dependent kinase inhibitor 1C (p57 Kip2) BWCR CDKN1C p57Kip2 p57 |
|---|---|
| Target | p57 Kip2 |
| Tissue Specificity | At least three isoforms of CDKN1C are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, CDKN1C often migrates at 57kDa in SDS-PAGE. CDKN1C antibody is predicted to not cross react with other CIP/KIP prot |
Application
Immunofluorescence of CDKN1C in 293 cells with CDKN1C antibody at 20 ug/mL.
Application
Western blot analysis of CDKN1C in 293 cell lysate with CDKN1C antibody at (A) 1 and (B) 2 ug/mL.| Application Notes | WB: 1 - 2 ug/ml. IF: 20 ug/ml: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
