Application
Application| Product Name | p63 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to p51BThe p53 tumor suppressor gene, which is induced by DNA damage and /or stress stimuli, causes cells to undergo G1-arrest or apoptotic death. p51 protein is similar but distinct from p53. Unlike ubiquitous expression of p53, expression of p51 is restricted to skeletal muscle, placenta, mammary gland, prostrate, trachea, thymus, salivary gland, uterus, heart and lung. p51 has two major splice variants p51A that contains 448 amino acids and p51B that contains 641 amino acids. In p53-deficient cells, p51A indices growth suppression and apoptosis. Mutations in p51 have been found in some human epidermal tumors. |
| Immunogen | Synthetic peptide: CNFDMDARRNKQQRIKEEGE (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| ICC: Use at a dilution of 1/300. WB: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | AIS B(p51A) B(p51B) EEC3 KET LMS NBP OFC8 RHS SHFM4 TP53CP TP53L TP73L p40 p51 p53CP p63 p73H p73L |
|---|---|
| Target | p51B |
| Tissue Specificity | This antibody is specific for p51B. It does not cross react with p51A |
Application
Application| Positive Control | Human Cell Line K562. |
|---|---|
| Application Notes | ICC: Use at a dilution of 1/300. WB: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 to -80 °C |
| Storage Buffer | PBS, 1mg/ml BSA, 0.1% sodium azide, pH7.2 |
