Rabbit polyclonal antibody to PACE4The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Immunogen
Synthetic peptide: internal domain of human PACE4.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
Immunohistology - Paraffin: 15 - 25 ug/ml Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PCSK6 SPC4 proprotein convertase subtilisin/kexin type 6
Target
PACE4
Tissue Specificity
This antibody detects an epitope within the internal region of human Paired basic amino acid cleaving system 4 (PACE4).
Application
Application
IHC-P analysis of human brain tissue using PACE4 antibody.
Application Notes
Immunohistology - Paraffin: 15 - 25 ug/ml Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.