Rabbit Polyclonal antibody to PACS1This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
Immunogen
PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 - 2 ug/ml:
Species Reactivity
Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MRD17 phosphofurin acidic cluster sorting protein 1
Target
PACS1
Tissue Specificity
PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
Application
Application
Western blot analysis of PACS1 in rat bladder tissue lysate with PACS1 antibody at 1 ug/ml.
Application Notes
WB: 1 - 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Storage Buffer
PACS1 antibody is supplied in PBS containing 0.02% sodium azide.