| Product Name | PACS2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PACS2 (phosphofurin acidic cluster sorting protein 2)Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human PACS2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Zebrafish, Xenopus laevisHuman (100%), Mouse (92%), Zebrafish (81%), Xenopus laevis (83%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FLJ25488 antibody KIAA0602 antibody PACS1L antibody PACS2 antibody phosphofurin acidic cluster sorting protein 2 antibody PACS1-like protein antibody |
|---|---|
| Target | PACS2 |
| Molecular Weight(MW) | 98 kDa (note) |
| Cellular Localization | Endoplasmic reticulum lumen , Mitochondrion |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
