| Product Name | PAI-1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3E529] to PAI-1PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type palsminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder. |
| Immunogen | Recombinant full length protein: human PAI. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | 3E529 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | nexin Endothelial plasminogen activator inhibitor PAI1 PLANH1 Plasminogen activator inhibitor-1 Plasminogen activator inhibitor1 Clade E serine (or cysteine) proteinase inhibitor PAI PAI-1 PAI 1 |
|---|---|
| Target | PAI-1 |
| Tissue Specificity | PAI1 antibody [3E529] () recognizes both free and complexed forms of Human PAI1. |
| Cellular Localization | Secreted |
| Application Notes | ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: 50mM Sodium phosphate, 100mM Sodium chloride, 1mM EDTA. pH 6.6 |
