Rabbit polyclonal to pan Synuclein predilutedSynucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha, beta and gamma synucleins. The alpha- and beta synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma synuclein protein is found primarily in the peripheral nervous system and retina but its expression in breast tumors is a marker for tumor progression.
Immunogen
A synthetic peptide corresponding to near N-terminal of human alpha, beta, pan-Synuclein protein.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
IHC-P: Working dilution: ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanRat
Concentration
1mg/ml
Target Information
Gene Synonyms
NACP Non A-beta Component Of AD Amyloid PARK1 PARK4 PD1 SNCA Synuclein Alpha (Non A4 Component Of Amyloid Precursor)
Target
pan Synuclein
Cellular Localization
Cytoplasmic
Application
Application
Application
Application
Human brain stained with
Application
Human Brain stained with anti-Synuclein-pan antibody
Positive Control
Brain
Application Notes
IHC-P: Working dilution: ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution and store at 4°C. Do not freeze.
Storage Buffer
PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide