Mouse monoclonal antibody [A6.4.12] to PARPThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Immunogen
Human PARP
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
A6.4.12
Host Species
Mouse
Tested Applications
ELISAICC/IFIHC-FIHC-PIPWB
Western Blotting: 1/1000 - 1/5000 Optimal dilution / concentration should be determined by the end user.:
This antibody recognizes poly (ADP-ribose) polymerase 1 (PARP).
Application
Application
WB analysis of HEK293 cell lysate using PARP antibody [A6.4.12].
Application
WB analysis of HeLa nuclear extract using PARP antibody [A6.4.12].
Application Notes
Western Blotting: 1/1000 - 1/5000 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.