Rabbit Polyclonal to PARP - 2Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Western blot - Use at 1:250 to 1:500 dilution. However, the investigator should determine the optimal dilution for a specific application.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Serum
Target Information
Target
PARP2
Tissue Specificity
Reacts with residues 43-59 of the 62 kDa human PARP-2 protein.
Application
Application
Western blot analysis of PARP-2 in 3T3 cell lysate.
Application Notes
Western blot - Use at 1:250 to 1:500 dilution. However, the investigator should determine the optimal dilution for a specific application.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.