Application
Western blot analysis of PCDH18 in Raji cell lysate with PCDH18 antibody at 2 ug/ml.Application
Immunofluorescence of PCDH18 in Mouse Brain cells with PCDH18 antibody at 20 ug/mL.Application
Immunohistochemistry of PCDH18 in mouse brain tissue with PCDH18 antibody at 2.5 ug/ml.| Product Name | PCDH18 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PCDH18Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development. At least three isoforms of PCDH18 are known to exist. This antibody is predicted to not cross-react with PCDH12. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Protocadherin18 Protocadherin 18 PCDH18 |
|---|---|
| Target | PCDH18 |
| Tissue Specificity | This antibody is specific for PCDH18 |
Application
Western blot analysis of PCDH18 in Raji cell lysate with PCDH18 antibody at 2 ug/ml.
Application
Immunofluorescence of PCDH18 in Mouse Brain cells with PCDH18 antibody at 20 ug/mL.
Application
Immunohistochemistry of PCDH18 in mouse brain tissue with PCDH18 antibody at 2.5 ug/ml.| Positive Control | Blocking Peptide: |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
