Application
PCDHB1 antibody detects PCDHB1 protein at membrane on mouse skin by immunohistochemical analysis. Sample: Paraffin-embedded mouse skin. PCDHB1 antibody dilution: 1:500.| Product Name | PCDHB1 antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PCDHB1 (protocadherin beta 1)This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PCDHB1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rhesus Monkey, ChimpanzeeHuman (100%), Rhesus Monkey (94%), Chimpanzee (99%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | protocadherin beta 1 PCDH-BETA1 |
|---|---|
| Target | PCDHB1 |
| Molecular Weight(MW) | 90 kDa (note) |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
Application
PCDHB1 antibody detects PCDHB1 protein at membrane on mouse skin by immunohistochemical analysis. Sample: Paraffin-embedded mouse skin. PCDHB1 antibody dilution: 1:500.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
